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There is no nature anymore

MIT Technology Review

No part of the globe is free of human fingerprints. Should we deploy technology to change it back? When people talk about "nature," they're generally talking about things that aren't made by human beings. But while there is plenty of God's creation to go around, it is hard to think of anything on Earth that human hands haven't affected. In the Brazilian rainforest, scientists have found microplastics in the bellies of animals ranging from red howler monkeys to manatees. In remotest Yakutia, where much of the earth remains untrodden by human feet, the carbon in the sky above melts the permafrost below.



Takeda's psoriasis pill developed with AI assistance succeeds in trials

The Japan Times

Takeda's psoriasis pill developed with AI assistance succeeds in trials Psoriasis is a chronic autoimmune disorder that causes rashes marked by itchy, scaly rashes and afflicts more than 125 million people worldwide. Takeda Pharmaceutical announced that its oral psoriasis drug zasocitinib proved safe and effective in late-stage trials, marking a milestone in its effort to treat the incurable skin condition and offset looming revenue pressure. Patients with moderate-to-severe plaque psoriasis who took the once-daily pill showed significantly clearer skin compared with those on placebo or the existing therapy apremilast, the company said in a statement Thursday. Takeda plans to submit data to the U.S. Food and Drug Administration and other regulators beginning in fiscal year 2026. If approved, zasocitinib would join the small but growing oral psoriasis treatments -- long a market dominated by ointments and injectable antibody therapies -- and stand out as one of the first drugs discovered with the help of artificial intelligence.



Russia-Ukraine war: List of key events, day 1,350

Al Jazeera

Is Trump losing patience with Putin? Will sanctions against Russian oil giants hurt Putin? Russian and Ukrainian troops have fought battles in the ruins of Pokrovsk, a transport and logistics hub in eastern Ukraine, with Ukraine's military reporting fierce fighting under way in a part of the city that was key for Kyiv's front-line logistics. Ukrainian President Volodymyr Zelenskyy said he visited troops fighting near the eastern city of Dobropillia, where Ukrainian forces are conducting a counteroffensive against Russian troops. Russia struck civilian energy and port infrastructure in a massive overnight drone attack on Ukraine's southern region of Odesa, the region's governor said in a post on the Telegram messaging app, adding that rescuers extinguished fires and there were no casualties.


A Self-Evolving AI Agent System for Climate Science

Guo, Zijie, Wang, Jiong, Ling, Fenghua, Wei, Wangxu, Yue, Xiaoyu, Jiang, Zhe, Xu, Wanghan, Luo, Jing-Jia, Cheng, Lijing, Ham, Yoo-Geun, Song, Fengfei, Gentine, Pierre, Yamagata, Toshio, Fei, Ben, Zhang, Wenlong, Gu, Xinyu, Li, Chao, Wang, Yaqiang, Chen, Tao, Ouyang, Wanli, Zhou, Bowen, Bai, Lei

arXiv.org Artificial Intelligence

Scientific progress in Earth science depends on integrating data across the planet's interconnected spheres. However, the accelerating volume and fragmentation of multi-sphere knowledge and data have surpassed human analytical capacity. This creates a major bottleneck for discovery, especially in climate science. To address this challenge, we introduce EarthLink, the first self-evolving AI agent system designed as an interactive "copilot" for Earth scientists. Through natural language interaction, EarthLink automates the entire research workflow by integrating planning, code execution, data analysis, and physical reasoning into a unified process that directly addresses this limitation. Beyond efficiency, it exhibits human-like cross-disciplinary analytical ability and achieves proficiency comparable to a junior researcher in expert evaluations on core large-scale climate tasks, including model-observation comparison and climate change understanding. When tasked with an open scientific problem, specifically the discovery of precursors of the Atlantic Niño, EarthLink autonomously developed a research strategy, identified sources of predictability, verified its hypotheses with available data, and proposed a physically consistent mechanism. These emerging capabilities enable a new human-AI research paradigm. Scientists can focus on value and result judgments, while AI systems handle complex data analysis and knowledge integration. This accelerates the pace and breadth of discovery in Earth sciences. The system is accessible at our website https://earthlink.intern-ai.org.cn.


Identifying internal patterns in (1+1)-dimensional directed percolation using neural networks

Parkhomenko, Danil, Ovchinnikov, Pavel, Soldatov, Konstantin, Kapitan, Vitalii, Chitov, Gennady Y.

arXiv.org Artificial Intelligence

In this paper we present a neural network-based method for the automatic detection of phase transitions and classification of hidden percolation patterns in a (1+1)-dimensional replication process. The proposed network model is based on the combination of CNN, TCN and GRU networks, which are trained directly on raw configurations without any manual feature extraction. The network reproduces the phase diagram and assigns phase labels to configurations. It shows that deep architectures are capable of extracting hierarchical structures from the raw data of numerical experiments.


STEPER: Step-wise Knowledge Distillation for Enhancing Reasoning Ability in Multi-Step Retrieval-Augmented Language Models

Lee, Kyumin, Jeon, Minjin, Jang, Sanghwan, Yu, Hwanjo

arXiv.org Artificial Intelligence

Answering complex real-world questions requires step-by-step retrieval and integration of relevant information to generate well-grounded responses. However, existing knowledge distillation methods overlook the need for different reasoning abilities at different steps, hindering transfer in multi-step retrieval-augmented frameworks. To address this, we propose Stepwise Knowledge Distillation for Enhancing Reasoning Ability in Multi-Step Retrieval-Augmented Language Models (StepER). StepER employs step-wise supervision to align with evolving information and reasoning demands across stages. Additionally, it incorporates difficulty-aware training to progressively optimize learning by prioritizing suitable steps. Our method is adaptable to various multi-step retrieval-augmented language models, including those that use retrieval queries for reasoning paths or decomposed questions. Extensive experiments show that StepER outperforms prior methods on multi-hop QA benchmarks, with an 8B model achieving performance comparable to a 70B teacher model.



OptimalThinkingBench: Evaluating Over and Underthinking in LLMs

Aggarwal, Pranjal, Kim, Seungone, Lanchantin, Jack, Welleck, Sean, Weston, Jason, Kulikov, Ilia, Saha, Swarnadeep

arXiv.org Artificial Intelligence

Thinking LLMs solve complex tasks at the expense of increased compute and overthinking on simpler problems, while non-thinking LLMs are faster and cheaper but underthink on harder reasoning problems. This has led to the development of separate thinking and non-thinking LLM variants, leaving the onus of selecting the optimal model for each query on the end user. We introduce OptimalThinkingBench, a unified benchmark that jointly evaluates overthinking and underthinking in LLMs and also encourages the development of optimally-thinking models that balance performance and efficiency. Our benchmark comprises two sub-benchmarks: OverthinkingBench, featuring simple math and general queries in 72 domains, and UnderthinkingBench, containing 11 challenging reasoning tasks along with harder math problems. Using novel thinking-adjusted accuracy metrics, we extensively evaluate 33 different thinking and non-thinking models and show that no model is able to optimally think on our benchmark. Thinking models often overthink for hundreds of tokens on the simplest user queries without improving performance. In contrast, large non-thinking models underthink, often falling short of much smaller thinking models. We further explore several methods to encourage optimal thinking, but find that these approaches often improve on one sub-benchmark at the expense of the other, highlighting the need for better unified and optimal models in the future.